What is Platelet-Rich Plasma (PRP)?
Platelet-rich plasma (PRP) is a treatment that harnesses your body’s own healing power. Platelets were once thought to have only one function: coagulation (blood clotting). However, we now understand that platelets are central to healing, acting as “the conductors of the symphony of healing.” PRP is created by drawing a small amount of your blood, concentrating the platelets, and injecting them into your knee joint to reset the joint environment.
Why is PRP Important for Knee OA?
- Shut down harmful inflammatory mediators, reducing chronic inflammation.
- Reprogram synoviocytes (the cells that produce joint fluid) to create healthier, more protective synovial fluid.
- Improve joint lubrication, reducing stiffness and discomfort.
- Help slow cartilage breakdown, protecting your knee from further damage.
How PRP Injections Help
Once injected into the knee, PRP works by:
✔ Calming inflammation—reducing pain and swelling over time.
✔ Stimulating healing factors—promoting a healthier joint environment.
✔ Restoring synovial fluid quality—making it more protective and cushioning.
✔ Encouraging tissue repair—potentially slowing OA progression.
How Long Do PRP Injections Work?
PRP benefits typically last 6-12 months, depending on the initial level of inflammation inside the knee. With regular treatments every 4-6 months, PRP can help maintain a healthier joint environment, slow cartilage loss, and keep you active until curative treatments become available.
What to Expect After Treatment
- Gradual improvement: PRP works over time, with pain relief and function improving over weeks to months.
- Better movement: Reduced stiffness supports easier movement and activity.
- Synergistic effects: PRP works best when combined with other treatments like HA injections and bracing.